U.S. flag

An official website of the United States government, Department of Justice.

NCJRS Virtual Library

The Virtual Library houses over 235,000 criminal justice resources, including all known OJP works.
Click here to search the NCJRS Virtual Library

Case of Sudden Infant Death Due to a Primary Cardiac Sarcoma

NCJ Number
242071
Journal
Journal of Forensic Sciences Volume: 57 Issue: 5 Dated: September 2012 Pages: 1368-1371
Author(s)
Fidelia Cascini, M.D., Ph.D.; Francesca Longo, M.D.; Dante Parenti, M.D.; Arnaldo Capelli, M.D.
Date Published
September 2012
Length
4 pages
Annotation
The case reported herein concerns the unexpected death of a 3-month-old female newborn who suddenly collapsed in her mother's arms and was dead on arrival at the hospital.
Abstract
The case reported herein concerns the unexpected death of a 3-month-old female newborn who suddenly collapsed in her mother's arms and was dead on arrival at the hospital. The clinical histories of the baby and her parents were negative for symptoms or signs of illness, even those of cardiovascular origin. Furthermore, no clinical appearance of a pathologic status was noted by pediatricians after the birth until the last emergency recovery. The autopsy excluded external and internal signs of violence but revealed a large primary cardiac tumor arising from the free wall of the left ventricle, which had totally invaded the heart causing mitral valve deformation. Histological examination showed a low-grade sarcoma that completely infiltrated the myocardial tissue. The pathogenesis of this sudden infant death was postulated as being owing to a fatal ventricular fibrillation combined with a tumor-related restrictive cardiomyopathy obstructing left ventricular filling. Abstract published by arrangement with John Wiley & Sons.