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Y-Chromosomal Microsatellite Diversity in Three Culturally Defined Regions of Historical Tibet

NCJ Number
239561
Journal
Forensic Science International: Genetics Volume: 6 Issue: 4 Dated: July 2012 Pages: 437-446
Author(s)
Tenzin Gayden; Areej Bukhari; Shilpa Chennakrishnaiah; Oliver Stojkovic; Rene J. Herrera
Date Published
July 2012
Length
10 pages
Annotation
This study analyzed 17 Y-STR loci in 350 Tibetan males from three culturally defined regions of historical Tibet: Amdo (88), Kham (109) and U-Tsang (153).
Abstract
A total of 299 haplotypes were observed, 272 (90.9 percent) of which were unique. Only one Y-STR profile is shared across the three Tibetan groups and, incidentally, is also the most frequent haplotype (4.0 percent), represented by two, five and seven individuals from U-Tsang, Kham and Amdo, respectively. The overall haplotype diversity for the three Tibetan populations at 17 Y-STR loci was 0.9978 and the corresponding values for the extended (11-loci) and minimal (9-loci) haplotypes were 0.9935 and 0.9909, respectively. Both neighbor-joining and Rst pairwise analyses suggest a close genetic relationship between the Amdo and Kham populations, while U-Tsang is genetically distinct from the aforementioned groups. The results demonstrate that the 17 Y-STR loci analyzed are highly polymorphic in all three Tibetan populations examined and hence useful for forensic cases, paternity testing and population genetic studies. (Published Abstract)