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Microhaplotypes in forensic genetics

NCJ Number
253976
Journal
Forensic Science International-Genetics Issue: 38 Dated: January 2019 Pages: 54-69
Author(s)
Fabio Oldoni; Kenneth K. Kidd; Daniele Podini
Date Published
January 2019
Length
16 pages
Annotation
Since microhaplotype loci (microhaps, MHs) are a novel type of molecular marker of less than 300 nucleotides, defined by two or more closely linked SNPs associated in multiple allelic combinations, the current review describes the features of these multi-SNP markers and documents their value in forensic genetics
Abstract

The review focused on individualization, biogeographic ancestry inference, and mixture deconvolution. Foreseeable applications also include missing person identification, relationship testing, and medical diagnostic applications. The technique is not restricted to humans. (publisher abstract modified)