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Methylenedioxypyrovalerone ("Bath Salts"),Related Death: Case Report and Review of the Literature

NCJ Number
Journal of Forensic Sciences Volume: 58 Issue: 6 Dated: November 2013 Pages: 1654-1659
Kilak Kesha M.D.; Cassie L. Boggs M.D.; Mary G. Ripple M.D.; Carol H. Allan M.D.; Barry Levine Ph.D.; Rebecca Jufer-Phipps Ph.D.; Suzanne Doyon M.D.; PaoLin Chi M.D.; David R. Fowler M.D.
Date Published
November 2013
6 pages
Cathinone derivatives bath salts have emerged as the latest drugs of abuse.
Cathinone derivatives bath salts have emerged as the latest drugs of abuse. 3,4-methylenedioxypyrovalerone MDPV is the primary active ingredient in bath salts used in this country. This article presents the second reported cause of death by MDPV intoxication alone. In April 2011, a delusional man was emergently brought to a hospital, where he self-reported bath salt usage. He became agitated, developed ventricular tachycardia, hyperthermia, and died. Comprehensive alcohol and drug testing was performed. Using the alkaline drug screen, heart blood contained 0.7 mg/L MDPV and peripheral blood contained 1.0 mg/L MDPV. His bizarre behavior with life-threatening hyperthermia was consistent with an MDPV-induced excited delirium state. MDPV is not yet found by routine immunoassay toxicology screens. Testing for MDPV should be considered in cases with a history of polysubstance abuse with stimulant type drugs, report of acute onset of psychogenic symptoms, excited delirium syndrome, or presentation in a hyperthermic state. Abstract published by arrangement with Wiley.