GEP-ISFG Collaborative Exercise on mtDNA: Reflections About Interpretation, Artefacts, and DNA Mixtures 2006

• NCJ Number: 222072
• Journal: Forensic Science International :Genetics Volume: 2 Issue: 2 Dated: March 2008 Pages: 126-133
• Author(s): L. Prieto; A. Alonso; C. Alves; M. Crespillo; M. Montesino; A. Picornell; A. Brehm; J.L. Ramirez; M.R. Whittle; M.J. Anjos; I. Boschi; J. Buj; M. Cerezo; S. Cardoso; R. Cicarelli; D. Comas; D. Corach; C. Doutremepuich; R.M. Espinheira; I. Fernandez-Fernandez; S. Filippini; Julia Garcia-Hirschfeld; A. Gonzalez; B. Heinrichs; A. Hernandez; F.P.N. Leite; R.P. Lizarazo; A.M. Lopez-Parra; M. Lopez-Soto; J.A. Lorente; B. Mechoso; I. Navarro; S. Pagano; J.J. Pestano; J. Puente; E. Raimondi; A. Rodriguez-Quesada; M.F. Terra-Pinheiro; L. Vidal-Rioja; C. Vullo; A. Salas
• Date Published: March 2008
• Length: 8 pages
• Publication Format: Article
• Publication Type: Report (Technical)
• Language: English
• Country: United States of America

Annotation

Results are presented of the seventh edition of the GEP-ISFG mitochondrial DNA (mtDNA) collaborative exercise.

Abstract

In general, the outcome of the GEP-ISFG consortium exercise reflects only a modest improvement in its global outcome; the knowledge acquired in previous editions regarding the most common causes of error helped to prevent the incidence of common mistakes in those laboratories with more experience. Most errors obtained were due to reading problems and misinterpretation of electropherograms, demonstrating that the lack of a solid devised experimental approach is the main cause of error in mitochondrial DNA (mtDNA) testing. GEP-ISFG mtDNA collaborative exercises have been performed in the last 7 years. One of the aims of these exercises is to improve the quality and standardization of mtDNA analyses in both technical and interpretation issues. This report presents the results of the seventh edition of the GEP-ISFG mtDNA collaborative exercise. Tables, appendix, references