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Fourier Transform Infrared Analyses of Some Particulate Drug Mixtures Using a Diamond Anvil Cell With a Beam Condenser and an Infrared Microscope

NCJ Number
136018
Journal
Journal of Forensic Sciences Volume: 37 Issue: 2 Dated: (March 1992) Pages: 467-487
Author(s)
E M Suzuki
Date Published
1992
Length
21 pages
Annotation
This article describes the techniques and advantages of using Fourier transform infrared analyses with a diamond anvil cell (DAC) to identify particulate drug mixtures.
Abstract
Although the DAC has been used in many forensic science laboratories for the analysis of trace evidence, few applications of this technique for the analysis of controlled substances have been reported. This may be due both to forensic drug chemists' unfamiliarity with this accessory and the nature and quality of spectra that result from use of a DAC on a dispersive instrument. Along with low-energy throughput, which results in relatively high noise levels, strong broad diamond absorption occur. With the use of a Fourier transform infrared instrument, these do not present a problem, and monogram quantities of materials can be analyzed when the DAC is used with an infrared microscope. Since single crystals can be sampled with the DAC, simple physical separations that involve particle-picking can be used in certain cases to isolate drugs from particulate mixtures for infrared analysis. This method is especially useful for some "difficult" mixtures and residues. Several examples of such analyses that involve samples of forensic science interest are presented. 11 figures and 39 references

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