Evaluation of Immunoassay Methods for Screening of Cocaine Metabolites in Urine

• NCJ Number: 128089
• Journal: Journal of Forensic Sciences Volume: 36 Issue: 1 Dated: (January 1991) Pages: 79-85
• Author(s): L D Baugh; E E Allen; R H Liu; J G Langner; J C Fentress; S C Chadha; L F Cook; A S Walia
• Date Published: 1991
• Length: 7 pages
• Publication Format: Article
• Publication Type: Research (Applied/Empirical)
• Language: English
• Country: United States of America

Annotation

Two immunoassay kits for conducting preliminary urine screening tests for cocaine, ARIA and TDX, were compared for correlation of their results as expressed in terms of equivalent benzoylecgonine concentration, with the gas chromotography/mass spectrometry (GS/MS) concentration of benzoylecgonine.

Abstract

The correlation coefficients, based on 62 highly relevant samples were 0.467 and 0.766 for ARIA and TDX respectively. The preliminary screen cutoff values were calculated based on the regressive equations; they were 380 and 190 mg/mL for ARIA and TDX, respectively. In relation to these cutoff values, ARIA generated 5 false negatives and 16 unconfirmed presumptive positives; TDX generated 3 false negatives and 6 unconfirmed presumptive positives. 2 tables, 2 figures, and 8 references (Author abstract modified)