Combined Ambient Ionization Mass Spectrometric and Chemometric Approach for the Differentiation of Hemp and Marijuana Varieties of Cannabis Sativa

• NCJ Number: 306221
• Journal: Journal of Cannabis Research Volume: 5 Issue: 5 Dated: Feb 2023
• Author(s): Megan I. Chambers; Samira Beyramysoltan; Samira Beyramysoltan; Benedetta Garosi; Rabi A. Musah
• Date Published: February 2023
• Length: 13 pages
• Grant Number(s): 2015-DN-BX-K057; 2017-R2-CX-0020; 2019-DU-BX-0026
• Sponsoring Agency: National Institute of Justice (NIJ)
• Corporate Author: Research Foundation of SUNY, University at Albany
• Publication Format: Article
• Publication Type: Research (Applied/Empirical)
• Language: English
• Country: United States of America

Annotation

The study presented here utilized DART-HRMS, for the first time, to investigate the complex genome-defined chemical fingerprints of hemp and marijuana (with no sample pretreatment) for the purpose of distinguishing between these two C. sativa varieties using multivariate statistical approaches.

Abstract

Advanced chemometrics was applied to the DART-HRMS data derived from commercial hemp, recreational marijuana, and marijuana samples from Drug Enforcement Administration (DEA)-registered suppliers to develop a robust model by which they (i.e., hemp and marijuana) could be readily differentiated. (Published abstract provided)