Detecting and quantifying cocaine in oral fluid is important for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used; however, spectroscopic methods were only applied to pretreated samples. The current study found that ultraviolet resonance Raman spectroscopy with 239-nm excitation can detect cocaine in oral fluid at 10 ìg/mL level. Further method development will be needed for reaching the practically useful levels of cocaine detection. (publisher abstract modified)
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