Unusual Case of Identification by DNA Analysis of Siblings

• NCJ Number: 237528
• Journal: Forensic Science International: Genetics Volume: 6 Issue: 1 Dated: January 2012 Pages: 121-123
• Author(s): Franz Neuhuber; Max P. Baur; Jan Cemper-Kiesslich; Bettina Dunkelmann; Fabio Monticelli
• Date Published: January 2012
• Length: 3 pages
• Publication Format: Article
• Publication Type: Case Study
• Language: English
• Country: Ireland

Annotation

This paper discusses DNA identification using samples from siblings.

Abstract

A badly decomposed body required identification by means of DNA analysis. A brother and sister of the deceased were available as reference subjects. Although investigation of Y-chromosomal markers established an exclusion condition, autosomal markers suggested a positive identification. In order to increase the reliability of the tests, X-chromosomal markers were also investigated. This analysis showed the body to have an XXY genotype (Klinefelter's syndrome). A number of hypotheses were assessed using biostatistical methods, ultimately resulting in a definite identification. The special aspect of Klinefelter's syndrome proved highly useful for biostatistical analysis. (Published Abstract)