PRELIMINARY OBSERVATIONS OF THE EFFECTS OF PHENCYCLIDINE IN DECOMPOSING TISSUES ON THE DEVELOPMENT OF PARASARCOPHAGA RUFICORNIS (DIPTERA: SARCOPHAGIDAE)

• NCJ Number: 146649
• Journal: Journal of Forensic Sciences Volume: 39 Issue: 1 Dated: (January 1994) Pages: 123-128
• Author(s): M L Goff; W A Brown; A I Omori; D A LaPointe
• Date Published: 1994
• Length: 6 pages
• Sponsoring Agency: American Acad of Forensic Sciences
• Publication Format: Article
• Publication Type: Report (Technical)
• Language: English
• Country: United States of America
• Note: Presented at the 45th annual meeting of the American Academy of Forensic Sciences, 1993, Boston

Annotation

Larvae of Parasarcophaga ruficornis (Fabricius) (Diptera: Sarcophagidae) were reared on tissues from rabbits administered different doses of phencyclidine to study the effects of this drug on insect development.

Abstract

Three rabbits were given 3.66, 7.31, and 14.62 mg of phencyclidine via ear vein infusion to produce different concentrations of phencyclidine in tissues. A fourth control rabbit received only normal saline by ear vein infusion. Immediately following death, a blood sample was taken from each rabbit and frozen for later analysis of drug content. In addition, liver samples were obtained from each rabbit and frozen for later analysis. No significant differences in larval growth were observed among colonies, although the duration of the nonfeeding portion of the third instar was shorter for larvae fed on tissues containing phencyclidine. Mortality during the larval stage was directly related to the phencyclidine dose administered. Puparial stage durations were longer for colonies fed on tissues containing phencyclidine, and the presence of phencyclidine was detected in larvae from all colonies fed on tissues from rabbits receiving the drug using gas chromatography/mass spectrometry. 15 references, 2 tables, and 1 figure