NCJ Number
132230
Journal
Crime Laboratory Digest Volume: 18 Issue: 2 Dated: (April 1991) Pages: 44-75
Date Published
1991
Length
32 pages
Annotation
These 1991 guidelines for a quality assurance program for DNA analysis are intended as a guide for laboratory managers to establish their own quality assurance program for Restriction Fragment Length Polymorphism (RFLP) DNA analysis laboratories.
Abstract
Guidelines for planning and organization pertain to goals, objectives, and authority and accountability. The guidelines for personnel pertain to job descriptions, qualifications, and task designations for each job position. Other guidelines concern the documentation on all significant aspects of the DNA analysis procedure as well as any related documents or laboratory records that are pertinent to the analysis or interpretation of results. Guidelines for validation cover general considerations for developmental validation of the DNA analysis procedure, characterization of loci, the specific developmental validation of RFLP procedures, the specific developmental validation of PCR based DNA procedures, and internal validation of established procedures. Other guidelines cover equipment, materials, and facilities; evidence-handling procedures; analytical procedures; case work documentation, interpretation, report writing, and review; proficiency testing; audits; and safety. 53 references and a glossary