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Developing Allelic and Stutter Peak Height Models for a Continuous Method of DNA Interpretation

NCJ Number
246375
Journal
Forensic Science International: Genetics Volume: 7 Issue: 2 Dated: February 2013 Pages: 296-304
Author(s)
Jo-Anne Bright; Duncan Taylor; James M. Curran; John S. Buckleton
Date Published
February 2013
Length
9 pages
Annotation
In this paper researchers describe a series of models that can be used to calculate expected values for allele and stutter peak heights, and their ratio SR.
Abstract

Traditional forensic DNA interpretation methods are restricted as they are unable to deal completely with complex low level or mixed DNA profiles. This type of data has become more prevalent as DNA typing technologies become more sensitive. In addition they do not make full use of the information available in peak heights. Existing methods of interpretation are often described as binary which describes the fact that the probability of the evidence is assigned as 0 or 1 (hence binary) (see for example [1] at 7.3.3). These methods are being replaced by more advanced interpretation methods such as continuous models. In this paper researchers describe a series of models that can be used to calculate expected values for allele and stutter peak heights, and their ratio SR. This model could inform methods which implement a continuous method for the interpretation of DNA profiling data. (Published Abstract)