The study found that the onset of gang membership significantly decreased anticipated substance-use guilt among both male and female respondents. This reduction was significantly associated with increased frequency of substance use only for female respondents, however, suggesting that gender moderates the mechanism through which gang membership influences substance use. After controlling for confounding using inverse propensity weighting, study results suggest that interventions aimed at reducing substance use by current and former female gang members should focus on the normative aspects of these behaviors. Criminologists are often concerned with identifying causal pathways for antisocial and/or delinquent behavior, but confounders of the exposure, mediator, and outcome often interfere with efforts to assess mediation. Many new approaches have been proposed for strengthening causal inference for mediation effects. The study methodology estimated a series of inverse propensity weighted models to obtain unbiased estimates of mediation in the presence of confounding of the exposure (i.e., gang membership) and mediator (i.e., anticipated guilt) using three waves of data from a multi-site panel study of a law-related education program for youth (n=1,113). (Publisher abstract modified)
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